A New Benzodioxan Derivative With Adrenergic Blocking Activity**LaWall Memorial Laboratory of Pharmacology and Biochemistry, Philadelphia College of Pharmacy and Science, Philadelphia 4, Pa

✍ Scribed by Victor Rossi, G. ;Rosenthal, Marvin E.

• Book ID: 102411661
• Publisher: Elsevier
• Year: 1959
• Weight: 377 KB
• Volume: 48
• Category: Article
• ISSN: 0095-9553
• DOI: 10.1002/jps.3030480713

✦ Synopsis

per 0s 4 28 40 72 Piperoxan 0.25 1. v. 1 0 100 0 Piperoxan 1 i. v. 2 0 reversal 26 Piperoxan 2 i. v. 1 16 reversal 85 A-2275 50 per 0s 5 38 42 80 a Epinephrine = 2 pg./Kg. of epinephrine hydrochloride, intravenously. b Carotid sinus occlusion = clamping both common carotid arteries for thirty seconds. Per cent decrease in pressor response based on an average of three responses prior to administration of compound A-2275 or piperoxan.