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A new asymmetric approach towards 2-pyrrolidinones and pyrrolidines: Simple versus double stereodifferentiation

โœ Scribed by Giovanni Poli; Simone Ciofi; Misa Maccagni; Nicola Sardone


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
286 KB
Volume
36
Category
Article
ISSN
0040-4039

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A new asymmetric approach toward 5-subst
โœ Giovanni Poli; Simone Ciofi Baffoni; Giuliano Giambastiani; Gianna Reginato ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 916 KB

The condensation between a chiral 2-silyloxypyrrole and either achiral or chiral formyl cation equivalents has been studied. The inethodolo~ has allowed Co build-up 5-substituted pyrrolidin-2-onc derivatives with a stereocontrol from good to excellent. The ehiral auxiliaD, located on the silylox.ypy