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A new aromatization of ring-A of steroids. Synthesis of estrone

โœ Scribed by Hiroshi Suginome; Hisanori Senboku; Shinji Yamada


Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
145 KB
Volume
29
Category
Article
ISSN
0040-4039

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A new strategy for introducing an hydroxy group at the position 3 of an aromatic A ring in a steroid, which is a key position for biological purposes, is described. This procedure has required a judicious choice of a t-butyl ether as protective group at the beginning of the synthesis, and its deprot