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A new approach to the study of lipid-protein interactions in the structure of biological membranes

✍ Scribed by Boris Yu. Zaslavsky; Anna A. Borovskaya; Aleksei Yu. Lisichkin; Yurii A. Davidovich; Sergei V. Rogozhin


Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
322 KB
Volume
24
Category
Article
ISSN
0009-3084

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✦ Synopsis


The lytic action of a number of N-acyl amino acids on lecithin liposomes was examined. The agents' affinity for the lecithin liposome membrane was measured and the results obtained were treated to estimate the interactions of the amino acid residues with the lecithin polar head group at the surface of the liposome membrane. The data were considered in relation to the study of the surfactant effects on the erythrocyte volume. The ability of the suggested approach to obtain information on protein-lipid interactions inaccessible by other techniques is briefly commented on.


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