A new approach to the synthesis of 4-(N-
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Alexander V. Stepakov; Michail A. Kinzhalov; Vitaly M. Boitsov; Liubov V. Stepak
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Article
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2011
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Elsevier Science
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French
⚖ 676 KB
Reaction of N-aryl substituted maleimides with aliphatic ketazines leads to the formation of 4,5-dihydropyridazin-3(2H)-ones in moderate yields. The reaction proceeds through 1,4-addition of an azine to the maleimide double bond, as confirmed by separation of the corresponding adducts in some cases,