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A new approach to synthesis of 3,3-dialkyl-3,4-dihydroisoquinoline derivatives

✍ Scribed by Yu. V. Shklyaev; M. A. Yeltsov; Yu. S. Rozhkova; A. G. Tolstikov; V. M. Dembitsky

Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 133 KB
Volume: 15
Category: Article
ISSN: 1042-7163
DOI: 10.1002/hc.20049

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✦ Synopsis

Abstract

The synthesis of 3,3‐dialkyl‐3,4‐dihydroisoquinolines via heterocyclization in three‐component reaction of an activated arene with isobutyraldehyde and nitriles is described. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:486–493, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20049

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