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A new approach to structure-activity using distance information content of graph vertices : A study with phenylalkylamines

✍ Scribed by G. Klopman; C. Raychaudhury; R.V. Henderson


Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
549 KB
Volume
11
Category
Article
ISSN
0895-7177

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A novel approach to the use of graph the
✍ Gilles Klopman; Chandan Raychaudhury 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 966 KB

In this article we describe a novel approach to the application of graph theory in structure-activity relationship studies. An information-theoretical topological index for the vertices of a molecular graph has been used for the qualitative evaluation of the mutagenic activity of a series of nonfuse