A New Approach to Oligonucleotide Labeling Using Diels—Alder Cycloadditions and Detection by SERRS.
✍ Scribed by Ljiljana Fruk; Antonio Grondin; W. Ewen Smith; Duncan Graham
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 53 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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Treatment of the dimethyl acetals of citral (1) and farnesal be subjected to a Diels-Alder reaction, which allows further synthetic elaboration. In particular, in the case of farnesal (2) with the superbase "LICKOR" in THF at low temperatures induces regioselective metallation at the allylic methyl