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A new approach to a complete robustness test of experimental nominal conditions of chemical testing procedures for internal analytical quality assessment

✍ Scribed by Luis Cuadros Rodrı́guez; Rosario Blanc Garcı́a; Ana M. Garcı́a Campaña; Juan M. Bosque Sendra


Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
169 KB
Volume
41
Category
Article
ISSN
0169-7439

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✦ Synopsis


The resistance presented by a particular analytical method or procedure to the generation of biased results when subjected Ž to slight modifications in nominal experimental conditions has traditionally been known as ruggedness from an interlabora-. Ž . tory trial or robustness from an intralaboratory study . This paper develops a protocol for a complete study of robustness, using a simple statistical technique which does not require the performance of ANOVA. The method simply consists of the Ž establishing of a standard calibration and the creation of experimental screening designs saturated fractioned or Plackettw Ž .

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