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A New Approach for the Conversion of Thiohydantoin to Hydantoin Derivatives

✍ Scribed by Ahluwalia, V. K; Mehta, Bhupinder; Rawat, Manju


Book ID
119958449
Publisher
Taylor and Francis Group
Year
1992
Tongue
English
Weight
197 KB
Volume
22
Category
Article
ISSN
0039-7911

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An improved and very simple procedure for thiazolinone conversion to thiohydantoin derivatives and their separation by reverse-phase high-pressure liquid chromatography is described. Trifluoroacetic acid (10%) in ethyl acetate has been employed as a conversion reagent to circumvent the deamidation o