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A New Anthraquinone and Two New Tetrahydroanthraquinones from the Roots of Prismatomeris connata

✍ Scribed by Shi-Xiu Feng; Jing Hao; Tao Chen; Samuel X. ;(Shengxiang) Qiu

Publisher
John Wiley and Sons
Year
2011
Tongue
German
Weight
198 KB
Volume
94
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

A new anthraquinone, 4‐hydroxy‐1,2,3‐trimethoxy‐6‐methylanthracene‐9,10‐dione (1), and two novel tetrahydroanthraquinones, prisconnatanones A and B (2 and 3, resp.), together with 15 known anthraquinones, 4–18, were isolated from the roots of Prismatomeris connata. Their structures were elucidated on the basis of spectroscopic data. Compounds 1–18 were evaluated for their cytotoxicity against A549 and LAC human cancer cell lines. Compound 2 and the anthraquinones with free OH groups exhibited activity against the test cell lines.

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