๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

A new and versatile synthetic route to 2-dimethylamino-3-alkyl and arylmethylene-2,3-dihydro-1H-isoindol-1-ones

โœ Scribed by Eric Deniau; Dieter Enders

Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
194 KB
Volume
43
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

A new synthetic route to highly enantioe
A new synthetic route to highly enantioenriched 3-substituted-2,3-dihydro-1H-isoindol-1-ones
โœ Eric Deniau; Dieter Enders; Axel Couture; Pierre Grandclaudon ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 164 KB

A concise and efficient synthesis of highly enantioenriched 3-alkyl and 3-aryl-2,3-dihydro-1H-isoindolinones is reported. The key step relies on the diastereoselective reduction of the N-acylhydrazonium salts generated by acidic treatment of hemiaminal precursors bearing the (S)-2-methoxymethylpyrro