𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A new and efficient palladium-catalyzed synthesis of a 2,3,4,5-tetrahydro-1H-2,4-benzodiazepine-1,3-dione derivative

✍ Scribed by Gabriele Bocelli; Marta Catellani; Federica Cugini; Raffaella Ferraccioli

Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
121 KB
Volume
40
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

Tic palladium-catalyzed intramolecular cyclization of l-butyl-l(o-iodobenzyl)-3-pheaylurea 1 at gO°C m the Ixesence of carbon monoxide at atmospheric pressure gives the corresl~nding 2,3,4,5-teWahydro-IH-2,4benzodiazepine-1,3-dione derivative 2 in 91% yield. Yield and selectivity are strongly affected by the solvent.

📜 SIMILAR VOLUMES

Synthesis of 1,3,3a,5-tetraaryl-3a,4,5,6
Synthesis of 1,3,3a,5-tetraaryl-3a,4,5,6-tetrahydro-3H-1,2,4-triazolo[4,3-a] [1,5]benzodiazepines
✍ Jiaxi Xu; Chenbo Wang; Qihan Zhang 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 104 KB

## Abstract A series of 3a,5‐diaryl‐1,3‐diphenyl‐3a,4,5,6‐tetrahydro‐3H‐1,2,4‐triazolo[4,3‐a][1,5]benzo‐diazepines was synthesized by the cycloaddition reactions of 2,4‐diaryl‐2,3‐dihydro‐1H‐1,5‐benzo‐diazepines and N‐phenylbenzonitrileimine generated from N‐phenylbenzenecarbohydrazonic chloride in

Reactions of 2,3-dihydro-1H-1,5-benzodia
Reactions of 2,3-dihydro-1H-1,5-benzodiazepines and chloroacetyl chlorides: Synthesis of 2a,3,4,5-tetrahydro-azeto [1,2-a][1,5] benzodiazepin-1(2H)-ones
✍ Jiaxi Xu; Gang Zuo; Wing Lai Chan 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 136 KB 👁 1 views

## Abstract 2a,4‐Disubstituted 5‐benzoyl‐2‐chloro/2,2‐dichloro‐2a,3,4,5‐tetrahydro‐azeto [1,2‐a] [1,5]benzodiazepin‐1 (2H)‐ones (**3a–h**) were synthesized by cycloaddition reactions of 2,4‐disubstituted 1‐benzoyl‐2,3‐dihydr o‐1__H__‐1,5‐benzodiazepines (**2a–h**) and ketenes, generated from chloro