✦ LIBER ✦

A new 99mTc labeled porphyrin for specific imaging of Sarcoma 120: Synthesis and biological study in a Swiss mouse model

✍ Scribed by S .J. Shetty; S. Murugesan; S. R. Chatterjee; S. Banerjee; T. S. Srivastava; O. P. D. Noronha; A. M. Samuel

Publisher: John Wiley and Sons
Year: 1996
Tongue: French
Weight: 252 KB
Volume: 38
Category: Article
ISSN: 0022-2135
DOI: 10.1002/(sici)1099-1344(199605)38:5<411::aid-jlcr858>3.0.co;2-w

No coin nor oath required. For personal study only.

✦ Synopsis

A new porphyrin m ~s o -5 , 1 0 , 1 5 , 2 0 -t e t r a k ~s ~3 , 4 -b I s ~c a r b o x y m e t h y l ~n e o x ~phanyllporphyrin (T3,48CPP) was synthesisrd and efficiently labeled w i t h 99mTc. On injecting thls 99mTc labeled porphyrin to abdoalnal Sarcoma 120 bearing Swiss mice I t accumulated in the abdominal tumour.

This radiolabeled complex can thus be used for tumour detection and diagnosls.