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A Neutral Molecule in a Cation-binding Site: Specific Binding of a PEG-SH to Acetylcholinesterase from Torpedo californica

โœ Scribed by Gertraud Koellner; Thomas Steiner; Charles B. Millard; Israel Silman; Joel L. Sussman


Book ID
117142860
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
182 KB
Volume
320
Category
Article
ISSN
0022-2836

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๐Ÿ“œ SIMILAR VOLUMES


Rapid binding of a cationic active site
โœ Sylvia Tara; Adrian H. Elcock; Paul D. Kirchhoff; James M. Briggs; Zoran Radic; ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 133 KB ๐Ÿ‘ 2 views

It is known that anionic surface residues play a role in the long-range electrostatic attraction between acetylcholinesterase and cationic ligands. In our current investigation, we show that anionic residues also play an important role in the behavior of the ligand within the active site gorge of ac