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A neurohormonal role for serotonin in the control of locust oviducts

✍ Scribed by Angela B. Lange

Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 196 KB
Volume: 56
Category: Article
ISSN: 0739-4462
DOI: 10.1002/arch.20010

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✦ Synopsis

Serotonin increases the frequency and amplitude of spontaneous contractions and leads to an increase in the basal tonus of the locust oviducts. These effects were dose-dependent and were seen on both the non-innnervated and innervated portion of the oviducts. Vertebrate type serotonin agonists and antagonists were used and the profile shows that the receptors on the non-innervated and innervated portion of the oviducts are more similar to 5-HT3 receptors than to either 5-HT1 or 5-HT2 receptors. No serotonin was found associated with the oviducts or the innervation to the oviducts using immunohistochemistry and HPLC coupled to electrochemical detection, suggesting a neurohormonal role for serotonin in the control of locust oviducts.

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