A Naturalistic Prospective Study of the Use of Fluoxetine in General Psychiatric Outpatients

✍ Scribed by C. MORTIMORE; C. V. R. BLACKER

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 716 KB
• Volume: 11
• Category: Article
• ISSN: 0885-6222
• DOI: 10.1002/(sici)1099-1077(199609)11:5<365::aid-hup815>3.0.co;2-f

✦ Synopsis

Two hundred and forty-eight consecutively recruited patients attending a general psychiatry clinic with a wide variety of psychiatric disorders were treated with fluoxetine for a minimum of 3 months. Fluoxetine was shown to be effective and well-tolerated in a number of conditions of which only 57 per cent were major depressive disorder. Specific conditions and/or the presence of co-morbid Conditions believed to be due to underlying disturbances in serotonin metabolism were associated with a significantly enhanced response. In contrast, significantly more patients who did not have such morbidity or co-morbidity appeared to be made worse by treatment with fluoxetine. The implications of this for clinical practice are discussed.