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A narrow therapeutical window of a nitric oxide synthase inhibitor against transient ischemic brain injury

✍ Scribed by Toshiaki Nagafuji, ; Masakazu Sugiyama, ; Toru Matsui, ; Tohru Koide,


Book ID
122979160
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
399 KB
Volume
248
Category
Article
ISSN
0926-6917

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## Abstract We have reported previously the delayed and differential induction of p38α and p38β mitogen‐activated protein kinases (MAPKs) in microglia and astrocytes, respectively, in brain after transient global ischemia. We report here the sustained induction and activation of p38α MAPK in activa