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A myoglobin evolved from indoleamine 2,3-dioxygenase

โœ Scribed by Tomohiko Suzuki; Takashi Takagi


Book ID
115985768
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
599 KB
Volume
228
Category
Article
ISSN
0022-2836

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## Abstract The first and rateโ€limiting step of the kynurenine pathway, in which tryptophan (Trp) is converted to __N__โ€formylkynurenine is catalyzed by two hemeโ€containing proteins, Indoleamine 2,3โ€dioxygenase (IDO), and Tryptophan 2,3โ€dioxygenase (TDO). In mammals, TDO is found exclusively in liv