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A mutational analysis of DNA mimicry by ocr, the gene 0.3 antirestriction protein of bacteriophage T7

โœ Scribed by Augoustinos S. Stephanou; Gareth A. Roberts; Mark R. Tock; Emily H. Pritchard; Rachel Turkington; Margaret Nutley; Alan Cooper; David T.F. Dryden


Book ID
116297740
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
214 KB
Volume
378
Category
Article
ISSN
0006-291X

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Dissection of the DNA Mimicry of the Bac
โœ Augoustinos S. Stephanou; Gareth A. Roberts; Laurie P. Cooper; David J. Clarke; ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 895 KB

The homodimeric Ocr (overcome classical restriction) protein of bacteriophage T7 is a molecular mimic of double-stranded DNA and a highly effective competitive inhibitor of the bacterial type I restriction/modification system. The surface of Ocr is replete with acidic residues that mimic the phospha