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A mutation in the gene for δ-aminolevulinic acid dehydratase (ALAD) causes hypochromic anemia in the medaka, Oryzias latipes

✍ Scribed by Daigo Sakamoto; Hisaaki Kudo; Keiji Inohaya; Hayato Yokoi; Takanori Narita; Kiyoshi Naruse; Hiroshi Mitani; Kazuo Araki; Akihiro Shima; Yuji Ishikawa; Yoshiyuki Imai; Akira Kudo


Book ID
119327264
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
298 KB
Volume
121
Category
Article
ISSN
0925-4773

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In the medaka fish (Oryzias latipes) many mutants for body color have been isolated. A typical example is the recessive oculocutaneous albino mutant i, which has amelanotic skin and red-colored eyes with no tyrosinase activity. To cast light on the molecular basis of the albino mechanism, we perform