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A mutation altering the function of a carbohydrate binding protein blocks cell–cell cohesion in developing Dictyostelium discoideum

✍ Scribed by Ray, Jasodhara; Shinnick, Thomas; Lerner, Richard


Book ID
109713991
Publisher
Nature Publishing Group
Year
1979
Tongue
English
Weight
860 KB
Volume
279
Category
Article
ISSN
0028-0836

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Identification of a hyaluronic acid (HA)
✍ C.A. Vines; M.W. Li; X. Deng; A.I. Yudin; G.N. Cherr; J.W. Overstreet 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 213 KB

## Abstract The macaque sperm surface protein PH‐20 is a hyaluronidase, but it also interacts with hyaluronic acid (HA) to increase internal calcium ( [Ca^2+^]~i~ ) in the sperm cell. A region of the PH‐20 molecule, termed Peptide 2 (aa 205–235), has amino acid charge homology with other HA binding