High-activity catechol-O-methyltransfera
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Vandenbergh, David J.; Rodriguez, Lawrence A.; Miller, Ivan T.; Uhl, George R.;
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Article
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1997
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John Wiley and Sons
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English
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Allelic variants at the catechol-O-methyltransferase (COMT) locus are candidates to contribute to genetic components of interindividual differences in vulnerability to substance abuse. COMT plays a prominent role in dopaminergic circuits important for drug reward, and COMT alleles encode enzymes who