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A mutant PSEN1 causes dementia with lewy bodies and variant Alzheimer's disease

โœ Scribed by Atsushi Ishikawa; Yue-Shan Piao; Akinori Miyashita; Ryozo Kuwano; Osamu Onodera; Hiroaki Ohtake; Masahiro Suzuki; Masatoyo Nishizawa; Hitoshi Takahashi


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
393 KB
Volume
57
Category
Article
ISSN
0364-5134

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## Abstract Seeking antemortem markers to distinguish Dementia with Lewy bodies (DLB) and Alzheimer's disease (AD), we examined brain glucose metabolism of DLB and AD. Eleven DLB patients (7 Lewy body variant of AD [LBVAD] and 4 pure diffuse Lewy body disease [DLBD]) who had antemortem position emi

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Objectives. To compare patients fulยฎlling clinical criteria for Lewy body dementia with those meeting clinical criteria for Alzheimer's disease. Design. Prospective cohort study. Setting. Psychiatric services and a memory clinic. Sample. 124 patients with DSM-III-R dementia. Measures. The assess