A murine model for assessing the respiratory hypersensitivity potential of chemical allergens
β Scribed by Toshihiko Satoh; Jean A. Kramarik; David J. Tollerud; Meryl H. Karol
- Book ID
- 118411778
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 836 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0378-4274
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π SIMILAR VOLUMES
The mouse IgE test is a novel approach to the predictive identification of chemicals that have the potential to cause sensitization of the respiratory tract. The method is based upon measurement of induced changes in the serum concentration of IgE in BALBlc strain mice following topical exposure to
## Abstract A variety of chemicals can cause sensitization of the respiratory tract and occupational asthma that may be associated with IgE antibody production. Topical exposure to chemical respiratory allergens such as trimellitic anhydride (TMA) has been shown previously to induce increases in th