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A multiplex RT-PCR assay for the detection of chimeric transcripts encoded by the risk-stratifying translocations of pediatric acute lymphoblastic leukemia

✍ Scribed by Scurto, P; Rocha, M Hsu; Kane, J R; Williams, W K; Haney, D M; Conn, W P; Shurtleff, S A; Downing, J R

Book ID
110054029
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
438 KB
Volume
12
Category
Article
ISSN
0887-6924

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## Abstract ## Background The classification of B‐lineage acute lymphoblastic leukemia (ALL) by specific chromosomal translocations may have prognostic implications. Reverse transcriptase‐polymerase chain reaction (RT‐PCR) assay is a useful tool for the detection of fusion transcript resulting fro