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A multimodal strategy for the treatment of patients with T2 invasive squamous cell carcinoma of the glottis

✍ Scribed by Ollivier Laccourreye; Eduardo M. Diaz Jr.; Vincent Bassot; Luca Muscatello; Dominique Garcia; Daniel Brasnu

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
84 KB
Volume
85
Category
Article
ISSN
0008-543X

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✦ Synopsis

BACKGROUND.

The current conservative standard of care for T2 squamous cell carcinoma of the glottis is either partial laryngectomy or radiation therapy.

METHODS.

Based on an inception cohort of 100 patients with T2 squamous cell carcinoma of the glottis and a minimum of 3 years of follow-up, the present study documented the results achieved with a multimodal strategy using platinum-based induction chemotherapy and partial laryngeal surgery. Statistical analysis of survival and local control was based on the Kaplan-Meier actuarial life table method.

Univariate analysis was performed to determine whether there was a correlation among various factors and toxicity, clinical response, histologic regression, local control, and survival.

πŸ“œ SIMILAR VOLUMES

Local recurrence after vertical partial
Local recurrence after vertical partial laryngectomy, a conservative modality of treatment for patients with Stage I–II squamous cell carcinoma of the glottis
✍ Ollivier Laccourreye; Raimundo Gutierrez-Fonseca; Dominique Garcia; StΓ©phane Han πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 95 KB πŸ‘ 2 views

## BACKGROUND. Based on an inception cohort of 103 patients who had local recurrence (Group I) and a witness group of 311 patients who achieved local control (Group II) after vertical partial laryngectomy for Stage I-II glottic carcinoma, the current retrospective study documented the consequences