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A multigenic approach to predict breast cancer risk

✍ Scribed by Armin Gerger; Uwe Langsenlehner; Wilfried Renner; Werner Weitzer; Tanja Eder; Babak Yazdani-Biuki; Günter Hofmann; Hellmut Samonigg; Peter Krippl

Book ID: 106377303
Publisher: Springer US
Year: 2006
Tongue: English
Weight: 151 KB
Volume: 104
Category: Article
ISSN: 0167-6806
DOI: 10.1007/s10549-006-9408-4

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## Abstract ## BACKGROUND Although the identification of the __BRCA1__ and __BRCA2__ genes have been of great interest, these genes account for less than 5% of all breast carcinoma cases. The remaining cases are sporadic. Reanalysis of a large twin study suggested that genetic factors may play a s