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A multicenter, randomized, double-blind dose-response evaluation of step-2 guanfacine versus placebo in mild to moderate hypertension

✍ Scribed by Barry J. Materson; Woodrow B. Kessler; Michael H. Alderman; Frank L. Canosa; Frank A. Finnerty; Stephen V. Savran; James I. McMillen; Anthony M. Marlon


Book ID
115672500
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
700 KB
Volume
57
Category
Article
ISSN
0002-9149

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We have compared the efficacy and pharmacokinetics of bisoprolol, a new cardioselective beta-adrenoceptor antagonist, with atenolol in a randomized double-blind crossover study in 12 patients (mean age 53.5 y) with mild to moderate essential hypertension. After a two week placebo wash-out period wit