A MULTI-CENTRE TRIAL OF POLLEN-TYROSINE ADSORBATE
โ Scribed by W. R. PALMER; A. BALACESCU
- Book ID
- 110883794
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 436 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0105-4538
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๐ SIMILAR VOLUMES
Analyses of multi-centre trials must consider the effects of the individual centres and the possibility of non-constancy of treatment effect differences among centres. This usually means an ANOVA with terms for centres, treatments, and centre;treatment interactions in practice, at least in the U.S.A
This paper examines the amount of variation among centres and estimates the overall e!ect of therapy in a multi-centre cancer clinical trial with censored failure time data. To investigate the centre e!ects, the variation in the treatment e!ect must be taken into consideration in addition to the var