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A mouse embryonic stem cell model for Schwann cell differentiation

✍ Scribed by Therese M. Roth; Poornapriya Ramamurthy; Fumi Ebisu; Kate F. Barald

Book ID
116975825
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
81 KB
Volume
295
Category
Article
ISSN
0012-1606

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## Abstract The neurofibromatosis Type 1 (NF1) gene functions as a tumor suppressor gene. One known function of neurofibromin, the NF1 protein product, is to accelerate the slow intrinsic GTPase activity of Ras to increase the production of inactive rasGDP, with wide‐ranging effects on p21ras pathw