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A more efficient method to generate integration-free human iPS cells

✍ Scribed by Okita, Keisuke; Matsumura, Yasuko; Sato, Yoshiko; Okada, Aki; Morizane, Asuka; Okamoto, Satoshi; Hong, Hyenjong; Nakagawa, Masato; Tanabe, Koji; Tezuka, Ken-ichi

Book ID
109935551
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
905 KB
Volume
8
Category
Article
ISSN
1552-4450

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## Abstract Transgenic and gene‐targeted mutant mice provide powerful tools for analysis of the cellular processes involved in early development and in the pathogenesis of many diseases. Here we describe a transgene integration strategy mediated by site‐specific recombination that allows establishm