A monovalent cation-selective channel of sheep cardiac muscle sarcoplasmic reticulum (SR)
β Scribed by A.J. Williams; M.A. Gray; Rap Montgomery
- Book ID
- 119441808
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 90 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0022-2828
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π SIMILAR VOLUMES
In order to study the conductances of the Sarcoplasmic Reticulum (SR) membrane, microsomal fractions from cardiac SR were isolated by differential and sucrose gradient centrifugations and fused into planar lipid bilayers (PLB) made of phospholipids. Using either KCl or K-gluconate solutions, a large
The purified ryanodine receptor channel of the sheep cardiac muscle sarcoplasmic reticulum (SR) membrane functions as a calcium-activated cation-selective channel under voltage-clamp conditions following reconstitution into planar phospholipid bilayers. We have investigated the effects of the tetra-