A molecular theory of sweet taste

✍ Scribed by Lemont B. Kier

• Publisher: John Wiley and Sons
• Year: 1972
• Tongue: English
• Weight: 444 KB
• Volume: 61
• Category: Article
• ISSN: 0022-3549
• DOI: 10.1002/jps.2600610910

✦ Synopsis

A study of several stereoselectively sweet amino acid molecules has led to a prediction of the presence and approximate location of a third structural feature, relative to the currently postulated A-H/B features in the glucophore. An examination of several unrelated sweet molecules supports this glucophore hypothesis. A relationship between a polarizability parameter and sweetness level in a series of substituted nitroanilines leads to the hypothesis that this third binding site may be involved in dispersion bonding with an appropriate receptor feature.

Keyphrases 0 Sweetness of molecules-molecular theory, three structural features 0 Molecular theory of sweetness-structural features, relationship between polarizability parameter and sweetness level 0 Amino acids-prediction of sweetness, molecular features Structure of molecules-prediction of sweetness 0

Glucophores-prediction of sweetness, three structural features