𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A molecular model of the folate binding site ofPneumocystis cariniidihydrofolate reductase

✍ Scribed by William M. Southerland


Publisher
Springer Netherlands
Year
1994
Tongue
English
Weight
618 KB
Volume
8
Category
Article
ISSN
0920-654X

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Molecular modelling of trimethoprim comp
✍ Ran Pan; Donnell Bowen; William M. Southerland πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 426 KB

Computer-assisted molecular modelling was used to generate structures for the trimethoprim (TMP):NADPH:dihydrofolate reductase (DHFR) ternary complexes for human wild-type DHFR and for five DHFR mutants (L22R, L22F, F31S, F31W and Q35P). The mutants correspond to DHFR proteins that have been isolate

Binding of the neuroleptic drug haloperi
✍ Jerry M. Anchin; Shankar Subramaniam; D. Scott Linthicum πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 813 KB

The ligand binding site of a monoclonal antibody (185), which binds the neuroleptic drug haloperidol, has been modelled using canonical structures and energy minimization techniques. This refined modelling protocol has allowed us to predict the variable region loop conformations. Three key residues,