The conformation of the heptacosapeptide hormone, gastrin releasing peptide, has been studied in buffer and in the presence of lipids, using static and dynamic fluorescence and CD. The results obtained show that, in buffer, the hormone exists in a collection of flexible, random coil type conformers,
A Molecular Model for the Inversion of the CD Spectra of Actinomycin D in the Presence of gem-diols
β Scribed by F. Ascoli; P. Desantis; M. Lener; M. Savino
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1972
- Tongue
- English
- Weight
- 314 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0006-3525
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β¦ Synopsis
A molecular model for the inversion of the CD spectra of actinomycin D in the presence of gem-diols is proposed, in terms of the inversion of chirality of the peptide groups directly connected to the phenoxazone ring.
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