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A molecular mechanism for mechanical activation of endothelial cells

โœ Scribed by Keigi Fujiwara; Michitaka Masuda; Masaki Osawa; Ken-ichi Kusano; Feng Shi; Tamlyn N Thomas


Book ID
116536191
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
67 KB
Volume
1262
Category
Article
ISSN
0531-5131

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Endothelial cell contacts control the permeability of the blood vessel wall. This allows the endothelium to form a barrier for solutes, macromolecules, and leukocytes between the vessel lumen and the interstitial space. Loss of this barrier function in pathophysiological situations can lead to extra