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A molecular basis for the two locus model of human complement component C4

✍ Scribed by Roos, M. H.; Mollenhauer, E.; Démant, P.; Rittner, C.

Book ID
109727373
Publisher
Nature Publishing Group
Year
1982
Tongue
English
Weight
630 KB
Volume
298
Category
Article
ISSN
0028-0836

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Complement component 3 (C3) is the central molecule of the complement system. It displays a number of polymorphic variants with, as yet, unclear functional consequences. We have investigated a number of rare C3 variants by PCR-SSCP (polymerase chain reaction-single strand conformation polymorphism)