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A molecular analysis of quinolone-resistant Haemophilus influenzae: Validation of the mutations in Quinolone Resistance-Determining Regions

โœ Scribed by Shoji, Hisashi; Shirakura, Tetsuro; Fukuchi, Kunihiko; Takuma, Takahiro; Hanaki, Hideaki; Tanaka, Kazuo; Niki, Yoshihito


Book ID
122990054
Publisher
Springer
Year
2014
Tongue
English
Weight
565 KB
Volume
20
Category
Article
ISSN
1341-321X

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Mechanism of Binding of Fluoroquinolones
โœ Sergio Madurga; Javier Sรกnchez-Cรฉspedes; Ignasi Belda; Jordi Vila; Ernest Giralt ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 675 KB

## Abstract We have studied the bacterial resistance to fluoroquinolones that arises as a result of mutations in the DNA gyrase target protein. Although it is known that DNA gyrase is a target of quinolone antibacterial agents, the molecular details of the quinoloneโ€“gyrase interaction remain unclea