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A Modular Assembly Strategy for Improving the Substrate Specificity of Small Catalytic Peptides

✍ Scribed by Tanaka, Fujie; Barbas, Carlos F.


Book ID
120320387
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
42 KB
Volume
124
Category
Article
ISSN
0002-7863

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Specificity of Lysine:N6-Hydroxylase: A
✍ L. Marrone; S. Siemann; M. Beecroft; T. Viswanatha πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 English βš– 231 KB

The recombinant cytoplasmic preparation of lysine : N 6 -hydroxlase catalyzes the conversion of L-lysine to its N 6 -hydroxy derivative when supplemented with the cofactors NADPH and FAD. A number of lysine analogs reflecting minor alterations in the inherent structural features of the amino acid as