✦ LIBER ✦

A modified definition of Sov, a segment-based measure for protein secondary structure prediction assessment

✍ Scribed by Adam Zemla; Česlovas Venclovas; Krzysztof Fidelis; Burkhard Rost

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 100 KB
Volume: 34
Category: Article
ISSN: 0887-3585
DOI: 10.1002/(sici)1097-0134(19990201)34:2<220::aid-prot7>3.0.co;2-k

No coin nor oath required. For personal study only.

✦ Synopsis

We present a measure for the evaluation of secondary structure prediction methods that is based on secondary structure segments rather than individual residues. The algorithm is an extension of the segment overlap measure Sov, originally defined by Rost et al. (J Mol Biol 1994;235:13-26). The new definition of Sov corrects the normalization procedure and improves Sov's ability to discriminate between similar and dissimilar segment distributions. The method has been comprehensively tested during the second Critical Assessment of Techniques for Protein Structure Prediction (CASP2). Here, we describe the underlying concepts, modifications to the original definition, and their significance.

📜 SIMILAR VOLUMES

Predictions of protein segments with the

Predictions of protein segments with the same aminoacid sequence and different secondary structure: A benchmark for predictive methods

✍ Irene Jacoboni; Pier Luigi Martelli; Piero Fariselli; Mario Compiani; Rita Casad 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 106 KB 👁 2 views