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A Model System for Regulation of Chronic HIV-1 Infection in Peripheral B Lymphocytes

โœ Scribed by Jeffrey Laurence; Bryn Grimison; Candido Rodriguez-Alfageme; Susan M. Astrin


Book ID
112269353
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
863 KB
Volume
196
Category
Article
ISSN
0042-6822

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## Abstract The ability of the antiโ€cancer drug, 9โ€Nitrocamptothecin (9NC), to inhibit replication of HIVโ€1 in clinically relevant primary lymphocytic cells was studied. Primary peripheral blood lymphocytes (PBLs) from a nonโ€infected donor were freshly infected with HIVโ€1 and treated with 9NC by us