𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A Model Substrate for Ellipsometry Studies of Lipoprotein Deposition at the Endothelium

✍ Scribed by Martin Malmsten; Günter Siegel; Angela Becker

Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
106 KB
Volume
240
Category
Article
ISSN
0021-9797

No coin nor oath required. For personal study only.

✦ Synopsis

Endothelial cell layers from umbilical cords were grown on methylated silica surfaces. Fluorescence microscopy showed this layer to be confluent and to consist of living cells. Initial ellipsometry measurements were performed to illustrate both the stability of the model surface in ellipsometry measurements and the Ca(2+)-dependent binding of lipoproteins at the cell-based substrate. The present substrate holds promise as a model substrate for in vitro investigations of lipoprotein deposition at the endothelium surface under close to in vivo conditions. Copyright 2001 Academic Press.

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