A Model Study for Constructing the DEF-Benzoxocin Ring System of Menogaril and Nogalamycin via a Reductive Heck Cyclization

Model Construction for the A–B–C Ring Sy

Model Construction for the A–B–C Ring System of Lysergic Acid via Vilsmeier–Haack-Type Cyclization of 1H-Indole-4-propanoic Acid Derivatives

✍ Masayuki Kurokawa; Toshiko Watanabe; Tsutomu Ishikawa 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 German ⚖ 192 KB

## Abstract __Vilsmeier–Haack__‐type cyclization of 1__H__‐indole‐4‐propanoic acid derivatives was examined as model construction for the A–B–C ring system of lysergic acid (**1**). Smooth cyclization from the 4 position of 1__H__‐indole to the 3 position was achieved by __Vilsmeier–Haack__ reactio