A model of the sodium dependence of dopamine uptake in rat striatal synaptosomes
β Scribed by D. D. Wheeler; A. M. Edwards; B. M. Chapman; J. G. Ondo
- Publisher
- Springer
- Year
- 1993
- Tongue
- English
- Weight
- 877 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0364-3190
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The relationship between circling behavior and the dopaminergic (DA) innervation of the striatum was investigated in rats. Vmax for DA uptake in crude mitochondrial (P2) fractions was used as a measure of the density of striatal DA terminals. Females, as a group, rotated away from (i.e., contralater
## Abstract The sodium dependence of Ξ³βaminobutyric acid (GABA) uptake has been studied in rat hypothalamic synaptosomes, and the results compared to previous studies in cortical synaptosomes. Initial velocity of GABA uptake was measured as a function of both GABA and sodium concentration, and thes