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A Model of Hyperhomocysteine-Induced Endothelial Dysfunction in Rats

✍ Scribed by M. V. Korokin; M. V. Pokrovskiy; O. O. Novikov; O. S. Gudyrev; V. V. Gureev; T. A. Denisyuk; L. V. Korokina; L. M. Danilenko; V. A. Ragulina; E. A. Konovalova; A. S. Belous

Publisher
Springer US
Year
2011
Tongue
English
Weight
348 KB
Volume
152
Category
Article
ISSN
0007-4888

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## Abstract ## Objective To investigate the effect of statins on vascular dysfunction in rat adjuvant‐induced arthritis (AIA). ## Methods Fluvastatin (5 mg/kg/day) was administered orally to rats with AIA, for 21 days after the onset of arthritis. The vasodilatory response to acetylcholine of ao