Dictyostelium discoideum slugs show a pronounced thermotaxis. We have modelled the motion of the D. discoideum slug in the absence and in the presence of a thermal gradient. Our model is an extension of the hybrid cellular automata/partial di!erential equation model, as formulated by Savill and Hoge
A Model of Dictyostelium discoideum Aggregation
β Scribed by O.O. Vasieva; B.N. Vasiev; V.A. Karpov; A.N. Zaikin
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 294 KB
- Volume
- 171
- Category
- Article
- ISSN
- 0022-5193
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β¦ Synopsis
The aggregation process in populations of Dictyostelium discoideum is mediated by cell communication through cyclic AMP (cAMP) signals and the chemotactic response of the cells to concentration gradients of cAMP. In the present paper several simple algorithms that describe cell behavior are used to create a model that correctly predicts the aggregation patterns of the cells. The formation of the aggregative structures with a definite geometrical characteristics can be studied by using the model.
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## Abstract We have purified actin and my osinβlike proteins from amoebae of Dictyostelium discoideum. These proteins are very similar in their physical and enzymatic properties to muscle actin and myosin. Most importantly, they form thin and thick filaments, respectively, and Dictyostelium actin a
## Abstract To find mutants of Dictyostelium discoideum that are unable to respond to exogenous cAMP signals (frigid mutants), amoebae of 218 independent aggregationβdeficient mutants were treated in suspension with artificial pulses of cAMP and screened for the capacity to form EDTAβresistant cohe