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A model for the function of the bisphosphorylated heart-specific troponin-I N-terminus

✍ Scribed by Kornelia Jaquet; Karin Lohmann; Thaddäus Holak; Michael Czisch; Jagdish Gulati; Ralph Jaquet


Book ID
110224259
Publisher
Springer Netherlands
Year
1998
Tongue
English
Weight
238 KB
Volume
19
Category
Article
ISSN
0142-4319

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The Ca(2+)/Mg(2+)-dependent interactions between TnC and TnI play a critical role in regulating the 'on' and 'off' states of muscle contraction as well as maintaining the structural integrity of the troponin complex in the off state. In the present study, we have investigated the binding interaction