Experimental observations of bacterial numbers employing high resolution electrical conductance measurements of the culture provide the basis for a proposed deterministic model of monophasic growth of populations in batch culture. The model postulates that the production and growth of each bacterium
A model for the control of the batch culture growth rate of enteric bacteria
β Scribed by P.R. Painter
- Publisher
- Elsevier Science
- Year
- 1976
- Tongue
- English
- Weight
- 614 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0022-5193
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β¦ Synopsis
It is shown that the growth of enteric bacteria can be reasonably well simulated by first-order differential equations. The equations express the notion that one or more classes of protein are rate-limiting under any condition of growth. The model is used to calculate the effect of regulatory mutations that impose a new protein burden on ceils, and the roles of genetic regulation and of feedback inhibition in maximizing the growth rate are discussed.
π SIMILAR VOLUMES
The specific growth rate (#) of a respirationdeficient mutant of Saccharomyces cerevisiae growing under defined experimental conditions in batch culture (mineral medium plus glucose and vitamins at 25 ~ C) varied from experiment to experiment over a wide range (0.10-0.24 h -1) and showed a normal di