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A model for phenotypic switching in adrenocortical cells senescing in culture

โœ Scribed by Peter J. Hornsby; Lianqing Yang

Book ID
119026383
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
653 KB
Volume
58
Category
Article
ISSN
0047-6374

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โœ Peter J. Hornsby; Kathy A. Aldern; Sandra E. Harris ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 973 KB

During cellular senescence, non-clonal cultures of bovine adrenocortical cells show a continuous decline in the rate of production of cyclic AMP (cAMP) stimulated by adrenocorticotropin (ACTH), without changes in the rate of forskolin- or prostaglandin E1-stimulated cAMP production. We investigated